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Researchers have found that excess levels of calcium in brain cells may lead to the formation of toxic clusters that are the hallmark of Parkinson’s disease.

A new super-resolution imaging technique allows researchers to track how surface changes in proteins are related to neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases.

Researchers have identified a new mechanism controlling brain development: that neurons not only ‘smell’ chemicals in their environment, but also ‘feel’ their way through the developing brain. 

Observation of the point at which proteins associated with Parkinson’s disease become toxic to brain cells could help identify how and why people develop the disease, and aid in the search for potential treatments.

How does the brain make connections, and how does it maintain them? Cambridge neuroscientists and mathematicians are using a variety of techniques to understand how the brain ‘wires up’, and what it might be able to tell us about degeneration in later life.

Researchers have built the first biologically realistic mathematical model of how the brain plans and learns when faced with a complex decision-making process.

Researchers have shown that graphene can be used to make electrodes that can be implanted in the brain, which could potentially be used to restore sensory functions for amputee or paralysed patients, or for individuals with motor disorders such as Parkinson’s disease. 

Delay mechanism within elegant brain circuit consisting of just five neurons means female crickets can automatically detect chirps of males from same species. Scientists say this example of simple neural circuitry could be “fundamental” for other types of information processing in much larger brains.

Researchers have identified how proteins that play a key role in Alzheimer’s disease are linked in a pathway that controls its progression, and that drugs targeting this pathway may be a potential new way of treating the disease.

Mutations might play a key role in the death of brain cells.